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Priorities on the Health Horizon José Manuel Sánchez Rivero a menudo bastante negativoPriorities on the Health Horizon In response to a growing national awareness that the development and use of new diagnostic, therapeutic, and preventive interventions had been occurring at a quickening paceone far outstripping the evidence necessary to make informed decisions about their comparative advantagethe Patient Centered Outcomes Research Institute (PCORI) was established in 2010 as part of the Affordable Care Act legislation. PCORI is guided